I'm getting some errors that I can't track down. I tried adjusting the time outs for the maria db connection but this doesn't look to be the issue so I figured I'd ask to see if anyone could offer some clues. The sites are running off of a read/replica setup with RDS Master / Replica databases. We use W3TC for caching with redis.
I've modified the IP, sites, and db links for privacy. Here are two examples, there are many other calls that are returning the same error Connection timed out,\n'errno' => 2002,\n'server_state' => up\n'lagged_status'
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[Thu Feb 20 11:45:38.841839 2020] [php7:notice] [pid 25575] [client fake_ip55.55.55.55:36330] WordPress database error 2020-02-20 16:45:38 Can't select global__r - \n'referrer' => 'www.example.com/wp-login.php',\n'server' => ,\n'host' => replica_db_link.com,\n'error' => Connection timed out,\n'errno' => 2002,\n'server_state' => up\n'lagged_status' => 3 for query SELECT wp_users.* FROM wp_users INNER JOIN wp_usermeta ON ( wp_users.ID = wp_usermeta.user_id ) WHERE 1=1 AND ( \n ( \n ( wp_usermeta.meta_key = 'wp_capabilities' AND wp_usermeta.meta_value LIKE '%\"administrator\"%' ) \n OR \n ( wp_usermeta.meta_key = 'wp_capabilities' AND wp_usermeta.meta_value LIKE '%\"editor\"%' ) \n OR \n ( wp_usermeta.meta_key = 'wp_capabilities' AND wp_usermeta.meta_value LIKE '%\"author\"%' )\n )\n) ORDER BY user_nicename ASC made by WP_User_Query::query`
and:
[Thu Feb 20 11:27:34.765842 2020] [php7:notice] [pid 38673] [client fake_ip55.55.55.55:56706] WordPress database error 2020-02-20 16:27:34 Can't select global__r - \n'referrer' => 'www.example.com/ads/recordmetrics/53251/rotation',\n'server' => ,\n'host' => replica_db_link.com,\n'error' => Connection timed out,\n'errno' => 2002,\n'server_state' => up\n'lagged_status' => 3 for query SELECT wp_users.* FROM wp_users INNER JOIN wp_usermeta ON ( wp_users.ID = wp_usermeta.user_id ) WHERE 1=1 AND ( \n ( \n ( wp_usermeta.meta_key = 'wp_capabilities' AND wp_usermeta.meta_value LIKE '%\"administrator\"%' ) \n OR \n ( wp_usermeta.meta_key = 'wp_capabilities' AND wp_usermeta.meta_value LIKE '%\"editor\"%' ) \n OR \n ( wp_usermeta.meta_key = 'wp_capabilities' AND wp_usermeta.meta_value LIKE '%\"author\"%' )\n )\n) ORDER BY user_nicename ASC made by WP_User_Query::query, referer: https://www.example.com/articles/article_name/`
select global__r
reveals jjj.blog/tag/global__r, note that if you're using HyperDB that's very important information to know that's missing from your question. Also keep in mind that W3TC support is offtopic here