The meta_query parameter always need to be an array of array ansand should be written like this
"meta_query" => array(
array(
"key" => "_fixtures",
"value" => $fixguid,
"compare" => "="
)
In fact, the array of array is use to serve to any relation when you want to query multiple metas, but it's need even you query only one.
Hope it works after !